4/30/2023 0 Comments Chemdoodle web components![]() ![]() ![]() SciFinder utilizes the ChemDoodle Web Components library from iChemLabs for the chemical sketcher and the ChemDoodle Java API from iChemLabs for SVG graphics output and other algorithms.ChemDoodle Web Components ChemDoodle Web Components Exploring ChemDoodle Web Components iChemLabs produces the popular ChemDoodle brand of chemical software, used by thousands of institutions in over 100 countries. IChemLabs, LLC is a scientific software company excelling in cheminformatics algorithms, visualization and graphics, and groundbreaking technologies such as HTML5/Canvas/WebGL. With more than 110 years’ experience, no one knows more about scientific information than CAS. ![]() Leverage our unparalleled content, specialized technology, and unmatched human expertise to customize solutions that will give your organization an information advantage. Scientific researchers, patent professionals and business leaders around the world across commercial, academic and government sectors rely on our solutions and services to advise discovery and strategy. Extending this integration to incorporate the full ChemDoodle desktop experience for our common customers will make it even easier for them to get the answers they need to optimize the productivity of their research.” About CASĬAS, a division of the American Chemical Society, partners with R&D organizations globally to provide actionable scientific insights that help them plan, innovate, protect their innovations, and predict how new markets and opportunities will evolve. “Many SciFinder n users have embraced the ChemDoodle experience already embedded in SciFinder n. “Chemists desire a seamless workflow experience, and CAS is committed to delivering that for our customers through partnerships with leading technology providers such as iChemLabs.” said Tim Wahlberg, Vice President of Product Management at CAS. Users can search patent and journal references by keywords, as well as by chemical structure or reaction, utilizing a state of the art, chemically aware relevance engine designed to provide fast access to the most relevant, actionable information, including step-by-step synthetic procedures and chemically annotated patent documents. SciFinder n provides the world’s most comprehensive and accurate collection of references, substances, reactions, and commercial suppliers curated by scientific experts. SciFinder n, the newest, most advanced member of the SciFinder ® family, provides scientists access to the latest disclosed research, enabling them to work more productively, creatively and confidently. By streamlining the communication between ChemDoodle and SciFinder n, this integration increases researchers’ efficiency and optimizes the workflow between these popular applications.” ![]() “Our focus is to provide the best experience for chemistry researchers. “We are proud to extend our collaboration with CAS to introduce a direct integration of our desktop ChemDoodle software with SciFinder n” said Kevin Theisen, President, iChemLabs, LLC. ChemDoodle has an easy-to-use interface for drawing molecules and reactions and with the ability to read many essential chemistry file formats, it facilitates quick investigation of chemical data across the vast SciFinder n content collection. Starting with ChemDoodle 10, new tools are included for directly querying substances, reactions, references and suppliers in SciFinder n. Built on the trusted CAS content collection, SciFinder n is a new caliber of chemical intelligence with remarkably relevant search, incredible ease of use and answers you can take right to the lab.ĬhemDoodle is a popular chemical drawing desktop application used by thousands of institutions in over 100 countries for creating publication-quality graphics, handling chemistry data and performing advanced cheminformatics functions. Advanced SciFinder n searches are now immediately accessible to ChemDoodle users to increase workflow efficiency.Ĭolumbus, Ohio (December 19, 2019) - CAS, a division of the American Chemical Society, continues its partnership with iChemLabs to optimize the efficiency of chemical structure searching and drawing in SciFinder n using ChemDoodle ®. ![]()
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4/30/2023 0 Comments Does melatonin increase deep sleep![]() ![]() ![]() Avidan, a professor of neurology and director of the Sleep Disorders Center at U.C.L.A. Hypnotic drugs like Ambien or Benadryl generally cause people to feel sleepy right away, and the sedation effect of those medications “far exceeds that which they obtain from melatonin,” said Dr. If you took melatonin in the middle of the day, it doesn’t really have that effect.” “If you took a sleeping pill in the middle of the day, it would make you feel sleepy. Martin, who is also a spokeswoman for the American Academy of Sleep Medicine. “The impact it has on our sleep depends on the time of day that you take it,” said Dr. ![]() Melatonin may make you feel a little drowsier when you take it, but it has a bigger impact on regulating the timing of your overall sleep-wake cycle and helping to set the circadian clock, the roughly 24-hour internal timekeeper that tells your body what time of day it is and syncs it with the outside world. Rosen, a sleep medicine doctor and associate professor of medicine at the Perelman School of Medicine at the University of Pennsylvania, “which is what I think is the misconception about how melatonin is used.” It doesn’t put you to sleep as much as it tells the body that it’s time to sleep. So taking a melatonin supplement is sort of like taking a dose of sunset, tricking your body into feeling like it’s nighttime. Instead of a lights-out trigger, melatonin acts more like a dimmer switch, turning the day functions off and switching night functions on. “Melatonin is sometimes called the ‘hormone of darkness’ or ‘vampire hormone,’” because it comes out at night, said Matthew Walker, a professor of neuroscience and psychology at the University of California, Berkeley, and the author of the book “ Why We Sleep.” As levels of melatonin rise, levels of cortisol, the stress hormone, fall. A few hours before our natural sleep time, as it starts to get dark outside and the light entering our retina fades, the gland switches on to flood the brain with melatonin. So what’s the best approach to taking melatonin? Here’s what experts had to say.ĭuring the day, the brain’s pea-sized pineal gland remains inactive. Melatonin, however, is relatively inexpensive and readily available at local pharmacies in the United States (in other countries it typically requires a prescription), and many people will go out and buy it on their own. Anxiety can cause insomnia, as can a host of other potentially serious ailments, such as sleep apnea, restless legs syndrome or mood disorders like depression, that may require medical treatment. “There are some clinical uses for it, but not the way that it’s marketed and used by the vast majority of the general public,” said Jennifer Martin, a psychologist and professor of medicine at the University of California, Los Angeles.Įxperts strongly urge people to consult their doctor or a sleep specialist before taking melatonin, in part because the supplement does not address many underlying health problems that may be disrupting sleep. But melatonin is also a hormone that our brains naturally produce, and hormones, even in minuscule amounts, can have potent effects throughout the body. Even the name of the popular dietary supplement sounds sleepy - that long “o” sound almost makes you yawn mid-word. Most people think of melatonin as a natural nod-off aid, kind of like chamomile tea in pill form. ![]() 4/30/2023 0 Comments Capto deae![]() ![]() The complexity of these media requires a more thorough process optimization study. In the polishing step of a two-step process, a multimodal chromatography medium capable of several interactions (e.g., hydrophobic, ion-exchange interactions, hydrogen bonding) can be used, which allows the selective removal of impurities like antibody aggregates, host cell proteins (HCPs), and leaked ligands. For particular antibodies, it is possible to apply a more efficient two-step process that involves one capture step and a single polishing step. First, the target is captured by chromatography with Protein A media, and two subsequent polishing steps are then performed according to a variety of protocols, often involving a combination of ion-exchange chromatography and hydrophobic interaction chromatography. Traditionally, MAbs are purified in a three-step process. A large experimental space can be investigated and characterized in a very short timeframe, enabling a better understanding of the effect of process conditions. HTPD uses a screening format to facilitate the identification of optimal experimental conditions by directed, rapid screening of experimental parameters. In this area, a new approach of high throughput process development (HTPD) is emerging as a useful tool for compliance with QbD. This initiative also is applicable to the development of downstream processes in the manufacture of monoclonal antibodies (MAbs). QbD stipulates a better understanding of the influence of raw materials and intermediates, and control of process parameters. The US Food and Drug Administration is also nudging the industry to implement its Quality by Design (QbD) initiative in the manufacturing processes. The use of the 96-well plate format enabled the efficient screening of three different media and optimization of chromatographic parameters to maximize yield at the desired purity level.īiopharmaceutical manufacturers are under increasing pressure to develop and produce biopharmaceuticals cost-effectively and within tight timelines. The most commonly used format for HTPD is the 96-well plate to facilitate rapid screening of chromatographic parameters. This article presents a case study illustrating the benefits of using a high throughput process development (HTPD) approach for choice of media and optimization of the polishing step of a monoclonal antibody in a two-step purification process. ![]() 4/30/2023 0 Comments Go car camera recorder![]() The camera system has WiFi for connecting to your smartphone or tablet, where the Blackvue app is used to set everything up, and GPS can be added as an optional extra. These are a light tighter than some other options out there, but should still be enough to capture a good outward view from most vehicles. The front-facing camera has a 139-degree lens and the rear is slightly narrower at 137 degrees. The footage is captured at 30 frames per second and there is a night vision mode to improve low-light recordings. It has a similar, cylindrical design to other Blackvue dash cams and records in Full HD 1080p resolution to the front and rear. You will likely want to get this professionally installed for the neatest result.Ī more affordable option from Blackvue, this is the company’s lowest-priced dual-camera system. It’s very much a set-it-and-forget-it design that doesn’t need interacting with once set up.Īs with other dual cameras, the Blackvue uses a long cable to connect the two together. Both cameras use a cylindrical design that makes them more compact than some others, and while this means they lack a display, this should make the system less distracting to the driver. There’s also a parking mode that uses motion and vibration sensors to detect events and record footage in a bid to catch evidence of vandalism or a parking incident. The data connection also enables two-way voice calls, where you can speak with whoever is in your car remotely. WiFi and GPS are both included, and Blackvue also sells an option 4G module to give the camera system an always-on data connection for remote notifications and live viewing. Both cameras record video at 60 frames per second, ensuring smooth footage. The front-facing field-of-view is 162 degrees while the rearview is a little tighter, at 139 degrees. The front-facing camera records in 4K resolution with an 8.0-megapixel sensor, while the smaller rear camera captures footage in Full HD. This is the current flagship front+rear dash cam set from Blackvue. There’s a 3.0-inch touchscreen on the rear and dual-band Wi-Fi for connecting to the companion smartphone app. It is worth noting how the rear camera is not compatible with the 512GW or the 380GWX.Ī top-notch dash cam, the Nextbase 622GW shoots in 4K through a polarising filter, or with slow motion at 120fps and 1080p if you so wish, and has features like Alexa and What3words built-in. The round shape means the camera can be positioned at almost any angle to ensure a good view of the road behind. The mount attaches to the rear windscreen using adhesive, then the ball-shaped camera snaps magnetically to the mount. ![]() Nextbase employs a magnetic mount for the rear camera. The rear camera has a 140-degree lens and comes with a cable that is six metres long which should be plenty to route discreetly around the interior, or through the roof lining, of most cars. ![]() Footage from both cameras is saved to a memory card inserted into the front-facing cam. We always say a higher resolution is better when it comes to dash cams, but which you buy here will of course depend on your budget. Lastly, the rear camera sticks to 720p HD when used with the 322GW dash cam. ![]() This is also true when connected to the 522GW and the 422GW, but with these there is also the option to lower the quality to 720p HD, which could be handy if you don’t want to quickly fill a smart microSD card with large files. When connected to the current Nextbase flagship, the 4K-shooting 622GW, the rear camera records at 1080p Full HD. But, similarly, the quality of the rear camera depends on which front-facing dash cam it is connected to. Like Thinkware, Nextbase also sells a rear camera that is compatible with a range of its dash cams. ![]() 4/30/2023 0 Comments Whirlpool duet dryer f01![]() ![]() Touch any key to clear the code from the display and return to the estimated time remaining.Ħ0 min is blinking or Extra Low light is blinking The dryer will continue to run when the is error is present. See also How long does an iPad Air last? What does AF mean on a dryer?Īn AF ( Restricted Air Flow) error code indicates that the lint screen or house vent is clogged the vent may be crushed, kinked or have too many turns. Unplug it (or turn off power at the circuit breaker), wait some time for the electrical charge to clear out of the dryer (usually 1 to 5 minutes at most), and then power it up again. After it has been reconnected to its power source, turn it back on and see if the error has been resolved.Īn AF ( Restricted Air Flow) error code indicates that the lint screen or house vent is clogged the vent may be crushed, kinked or have too many turns. It is recommended that you wait a few minutes before you plug it back in. To reset your Whirlpool dryer’s main control, simply unplug your dryer from its power source. ![]() Check sensor, sensor harness, and the sensor harness connection at sensor and oven control. For SELF CLEAN models, check door lock operation. ![]() If present, replace control board (clock). Whirlpool has released a full list of affected models on its website.į2 – Oven Temperature Is Too High – Check for welded contacts on bake and broil relays. Potentially faulty machines are sold under the brand names of Creda, Hotpoint, Indesit, Proline and Swan. Whirlpool said it has identified a potential risk with two types of tumble dryers manufactured between April 2004 and September 2018. You can easily fix this problem by removing any blockages from the drain pump situated at the front of the machine for easy access. Should the error code E3 appears it is warning that the machine is not draining. See also How do I delete a discussion post on Blackboard? ![]() 4/30/2023 0 Comments Usb block erupter profitability![]() ![]() There's only one tool in this thread, and it's the one recommending cgminer over bfgminer for Block Erupters. So bfgminer is for tools? It's very easy? How come then you've got 5 extra steps (that may or may not work) to get them working? open zadig > click list all devices > select cpx210 to uart controller > click reinstall driver > wait til it installs then exit zadig.Ģ. say 0.10 BTC then he might reach profitability within 60-90 days from now. If it still says failed to initialize after you've done these steps do this:ġ. OK, I have been seeing a lot of USB block erupter mining devices for sale and. > restart cgminer-nogpu.exe and presto you're mining. unplug block erupter(careful it may be hot) > restart computer > replug block erupter. > Press "W" to write your info to a config file. > after it loads and says USB FAILED to initialize hit "S" to bring up the settings menu. Wystarczu je podczy do portu USB i dziaaj i cign program do kopania. open and run cgminer-nogpu.exe >input pool url, username and password. Bitcoin Koparka ASIC Block Erupter USB 336MH/s BTC Zuywaj tylko 2,5 Wat, s bardzo ekonomiczne jak na swoj szybko. open zadig > click "list all devices" > select cpx210 to uart controller from drop down menu > click replace driver > wait til it installs then close zadig.ĥ. Use cgminer instead, version 3.3.1 or higher. There are also a few other investment factors to consider. There are some units like the 21 Bitcoin Computer that cost 150, which can technically be classified as a USB miner, but these are on the high end. In comparison, a USB ASIC miner costs less than 50 in most cases. I tried cgminer and bfgminer and even used the same parameters I used years ago but they don't seem to work anymore. A high-quality ASIC rig could cost over 3,000. Save your money, you’re better off buying BTC with it. They’re not for making money, they’re for tinkering with blockchain and proof of concept work, etc. I forgot I had the Erupter and found it today. The good ones make about 1 a day and cost about 1 in electricity to run. This is the best choice if you want to see how mining works, but just the like with most USB miners, a profit should be least expected. ![]() They have 330 MH/s of hash power which will give you less than 0.01 per month. The first Bitcoin USB miners were the Sapphire Block Erupters. 09160374 (currently 0.00053247 BTC)īased off of the current NMC exchange rate, my erupters have generated a total of 0.03101768-BTC in under 100 days.Īt the current BTC/USD exchange rate of $578.86, I've been able to generate $17.96 USD.BFGMiner is for tools. I know it's 2021 and pretty much impossible to solo mine with this and find a block (so you're saying there's a chance), but why not. ASICMiner Block Erupter USB 330MH/s Sapphire Miner. Altogether, a daily profit of about $0.15 per day USD.ĤxUSB erupters + $42.94 (USB Hub & Fan) + S&H = $106.16 In addition to the BTC, I generated about $0.03 in NMC. With the 4 erupters running 24/7, I use about $0.02/USD of electricity while generating on average $0.12-$0.16 in bitcoin per day. I chose mining because it seamlessly allows you to mine namecoin through the same port/pool.ĭon't use bitminter's flash miner if you want to mine alt coins with your gpus while going after bitcoin with the ASIC cards (it doesn't play nice if you have wallets running or cgminer working and you'll get a lot of rejects)- but by using a command line miner for sha-256, I can also run guiminer-scrypt or cgminer to hash out alt coins. The colors included blue, silver, black, red, and yellow. They were small, portable, yet relatively powerful miners, and were suggested as a perfect gift for getting people knowing about Bitcoin and Bitcoin mining. I've had a constant 1.3-1.4Gh/s with these USB erupters, peaking at 2.2Gh/s (but that's an anomaly and not constant) I use bfgminer and set them up to run They're super easy to use once you get the drivers set up and understand how to mine. Block Erupter USBs were first announced by friedcat on May 4th, 2013, on. I purchased 4 erupters back in November 2013- just to run beside my 4x5970s and 3x7950s, it was an experiment and at the time I was pretty new to mining in general.Ĥ-erupters with 92mm cooling fan and powered-USB hub. These are the same chips that are found on the Block Erupter USB devices, so they are not very power efficient nowadays as compared to other alternative. Realizing I'm very tardy to this post, I'd like to throw out this update for those currently googling this question. ![]() 4/30/2023 0 Comments Ken buck vs karen mccormick![]() ![]() "And if Ken Buck won't act to stop it, if elected to Congress, I will join colleagues on both sides of the aisle to do so. The family separation policy by the Trump Administration is wrong. "Faith leaders have spoken out against it, community leaders have spoken out against it, Moms have spoken out against it, and I am too. These are babies missing their mothers because the Trump Administration is using them for politics. "This is a choice by the Trump Administration to punish these kids and their parents for trying to do the right thing, and it is immoral. ![]() "As a Mom of three, I can't imagine trying to build a better life for my children only to have them taken away from me," said McCormick. ![]() Buck has actually blamed the family separation on the parents, many of whom are fleeing violence in their own countries and seeking asylum in the US. I will fight to ensure that our teachers and schools get the resources they need.As Ken Buck continues to advocate for the Trump Administration's cruel and unnecessary policy of separating parents from their children, Karen McCormick DVM continues to speak out against it. Fair tax reform will help more Americans build wealth and hang onto the earnings we work so hard for.Ī better school system: We simply can’t afford to continue neglecting our schools. What are two other issues that demand attention from Congress?Ī fair economy: We’re working harder than ever before, but incomes haven’t kept pace with our productivity or the cost of living. I support a public buy-in option for the popular and cost-effective Medicare system and harnessing the negotiating power of Medicare to reduce prescription drug costs. We can guarantee affordable healthcare to all Americans by using resources wisely, improving access and transparency, making it easier and more affordable for small businesses to provide insurance, and encouraging insurers and providers to compete. No American should face bankruptcy or fear losing their insurance due to illness or injury. What can be done to improve the nation’s health care system? Like any complex challenge, we need to seek out evidence-based solutions. My constituents have urged me to support a path to citizenship for DACA recipients and a federal guestworker program to help our district meet our labor needs. Like the vast majority of Coloradans, I support an immediate halt to the cruel separation of children from their families. We need comprehensive, bipartisan immigration reform, and cooperation in Congress is the only way to achieve lasting policies we can agree and rely on. What is your position on immigration reform? I support ongoing funding to Medicaid to help people recover, but my opponent’s plan to cut Medicaid would only worsen this crisis. We also need to hold drug manufacturers accountable for misleading patients. What should Congress do to address the nation’s opioid epidemic?Ĭongress should improve access to appropriate medical treatment to help people recover from addiction create a stronger nationwide Prescription Drug Monitoring Program with better training for medical professionals, and fight the factors that lead to addiction such as pain, poverty and depression. That’s exactly what I’ll work hard to do in Congress. Our large and diverse district needs a problem-solver, not a politician, and solving problems starts with compassion, cooperation and listening to what people actually want: Coloradans throughout our district have urged me to fight Washington corruption, secure affordable healthcare, create a fairer economy and bring good jobs to our state, improve our school system, strengthen our trade deals and protect our Colorado way of life. Campaign website: How would choosing you for this office improve the lives of residents of the district? ![]() 4/30/2023 0 Comments Adjustable window screens![]() ![]() ![]() To capture an open window, click the drop-down menu beside New, select Window Snip and click on any window. It's called the Snipping Tool and it's your best bet if you need more precise screen captures of only specific parts of your screen.Ĭlick the Start button, start typing "snipping tool" and click on the app to open it. Windows comes with screen-capture software installed, as well. Check the box beside Share screenshots using Dropbox.Click Preferences and open the Import tab.Click the settings drop-down in the upper right corner of the window that appears.Locate and right-click on the Dropbox icon.Open the Auto Save tab and check the box beside Automatically save screenshots I capture to OneDrive.Locate and right-click on the OneDrive icon.Click the Show hidden icons button in the Notification Area in the Taskbar.This feature saves any Alt + PrtSc captures as images without the need for pasting into Paint.Ĭaptures using the Print Screen key will be saved locally, either at OneDrive > Pictures > Screenshots or Dropbox > Screenshots, and automatically synced to your cloud storage. If you use Microsoft's OneDrive, which comes preinstalled, or Dropbox and have the application installed on your Windows machine, you can opt to have all screen captures saved to your cloud storage automatically. So when you use the Alt + PrtSc hotkey, you will still need to paste the capture into Paint and save it. Pressing Windows + Alt + PrtSc doesn't do anything at all. Sadly, this doesn't work with the Windows modifier key. This captures the current active window, so make sure to click inside the window you want to capture before pressing the key combination. If you want to capture just a single open window without everything else, hold Alt while pressing the PrtSc button. The problem is that this still captures the entire display - including a second monitor if you have one. Holding the Windows key and pressing the Print Screen button will save a screenshot as an image, removing the need to paste the capture into Paint to save it manually.īy default, these screen captures will be saved at This PC > Pictures > Screenshots. With Windows 10, a new screen capture hotkey combination was introduced. Here's how you can do it - without installing a new program. And, no, it doesn't require one of those expensive apps. There are easier and faster ways to grab your screen in Windows. But to save that screenshot, you need to paste it into Paint, where you can then crop and edit the screenshot and save it as an image. Pressing this key captures the entire screen (or multiple screens if you use more than one monitor) and copies it to the clipboard. There is a button dedicated to this on almost every keyboard called the Print Screen key (abbreviated as PrtSc or PrtScn). ![]() Using Windows, you'd think taking screenshots is simple. ![]() 4/30/2023 0 Comments Translucent definition![]() ![]() ![]() TCM diagnoses and try to treat bipolar and other depression related disorder from physiochemical understanding., whereas 5-element therapy does not treat body as it is concerned with spirit treatment and is completely different subject to understand and yes it has been reported to heal depression in many. To be simple let me say that TCM is similar to modern type of system as they try to link the diagnosis with the biochemical nature of the body. Can someone clear in simple term to make me understand-please? What makes TCM close to modern medicine and what are 5-element treatment and their role in depression and related disorders like bipolar.Ī. Can someone clear in simple term to make me understand-please? A difficult and new confusion struck me…. Of course, watch your cholesterol intake. But they are dangerous - they can cause severe bruising, uncontrolled bleeding, and uncontrolled unnoticed internal bleeding from the slightest trauma! The risk is simply not worth it. No! There are prescription blood thinners, etc, that are for people with much clogged arteries, who are at very high risk of stroke. ![]() But you know how some people think of something too much and untimately end up in worry. I want to know is there something out there like a pill or whatever to clear up your clogged arteries if that was the problem, I don't know why but I have this thing in my head that I have some blockage I did get checked and everything is good. I know we walk around this world feeling good and healthy but really don't know the truth of what is going on in our body. ![]() 4/30/2023 0 Comments Audirvana studio remote![]() ![]() After installing, Goto Start menu » Recommended section » Audirvāna Remote.On the results page, open and install Audirvāna Remote. After login, search "Audirvāna Remote" in search bar.Install Audirvāna Remote on Windows 11:.After installation, Goto Windows Start Menu or Apps list » Open the Amazon Appstore » Login (with Amazon account).It also automatically installs Windows Subsystem for Android. Check if there's a native Audirvāna Remote Windows app ».Processor: Intel Core i3 8th Gen, AMD Ryzen 3000 or Qualcomm Snapdragon 8c (minimum).This enables you browse and install android apps from a curated catalog. To use Audirvāna Remote mobile app on Windows 11, install the Amazon Appstore. Install Audirvāna Remote on your Mac using the same steps for Windows OS above. Once Audirvāna Remote is downloaded inside the emulator, locate/click the "All apps" icon to access a page containing all your installed applications including Audirvāna Remote.The search will reveal the Audirvāna Remote app icon.Open the Emulator app you installed » goto its search bar and search "Audirvāna Remote".On your computer, goto the Downloads folder » click to install Bluestacks.exe or Nox.exe » Accept the License Agreements » Follow the on-screen prompts to complete installation. Install the emulator on your PC or Mac:. ![]() Download Bluestacks Pc or Mac software Here >. We recommend Bluestacks because you can easily find solutions online if you run into problems while using it. Download an Android emulator for PC and Mac:. ![]() |
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